The Saint Vincents Comprehensive Cancer Center occupies 65,000 square feet in a renovated ground floor of the former Port Authority Building (circa 1930) at 111 Eighth Avenue in New York City. The renovation relocates and expands outpatient cancer diagnostic and treatment services of Saint Vincents Medical Center as a stand-alone facility that allows 24-hour access to diagnostic radiology, radiation oncology, chemotherapy, medical oncology, and outpatient surgery.

The development of organic sign shapes and the use of translucent materials, as well as the selection of color standards, all intended to be soft and inviting, were derived from the proportions, curved shapes, and materials of the interior architecture.

The project was recognized by Communication Arts for Design Excellence in Environmental Graphic Design.